Meeting clinical needs for and sidestepping supply chain threats to COVID-19 testing through continuous process improvement

نویسندگان

چکیده

Abstract Introduction/Objective The first human case of SARS-CoV-2 infection was reported in December 2019. By late February 2020 evidence community transmission the United States documented and soon it developed into a global pandemic. On March 11, 2020, Mayo Clinic Arizona’s Microbiology Laboratory introduced PCR test for diagnosis infection. Even as testing demands exponentially increased, hospital relied on timely results to assist directing patient care. In order provide face continuously emerging supply chain threats, we needed increase our capacity by reducing technologist time reagent waste, without impacting turnaround or other quality metrics such repeat rate. Methods/Case Report Technologist measured hands-on per specimen. Reagent use defined volume lysis buffer (the primary rate limiting due constraints) used sample. Turnaround from receipt lab until result verification rerun is percent specimens with an internal control (IC) failure, indicator specimen process quality. Unnecessary steps were determined using map, spaghetti diagram waste walk. Improvements included simplifying steps, changes protocols design. Impacts improvements 5 months post-implementation. Results (if Case Study enter NA) Process reduced sample 30.8 seconds decreased critical needs 23.6%. led $104,000 just savings over months. rates not negatively impacted. Conclusion creating leanest possible workflow, able meet accurate results. future workflows, will continue implement lean processes ensure most efficient limited resources.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Advancing health system integration through supply chain improvement.

Collaboration is a key element to success in the provision of sustainable and integrated healthcare services. Among the many initiatives undertaken to improve service quality and reduce costs, collaboration among hospitals in Ontario has been difficult to achieve; however, voluntary collaboration is vital to achieving transformation of the magnitude envisioned by system leaders.

متن کامل

Increasing Supply Chain Robustness through Process Flexibility and Strategic Inventory

This paper combines process flexibility and strategic inventory to develop an effective disruption mitigation strategy. We consider a manufacturer with multiple plants producing multiple products where strategic inventory can be held for any product. We measure the level of supply chain robustness by proposing the concept of Time-to-Survive (TTS) defined as the maximum time that no customer dem...

متن کامل

Increasing Supply Chain Robustness through Process Flexibility and Inventory

We study a hybrid strategy that uses both process flexibility and inventory to mitigate risks of plant disruption. In this setting, a firm allocates inventory before disruption while facing demand uncertainties; demand is realized after disruption, and the firm schedules its production using process flexibility to minimize lost sales. This interplay between process flexibility and inventory is ...

متن کامل

Antibodies testing, Immunity and immunity passport in Covid-19

The global outbreak of coronavirus disease-2019 (COVID-19) has affected most countries in the world. Our knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evolving, and it is important to have a clear understanding of the nature of the tests and the interpretation of their findings. In this paper, the purpose is to interpret the results of two typ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2021

ISSN: ['0002-9173', '1943-7722']

DOI: https://doi.org/10.1093/ajcp/aqab191.276